A Biphasic Apatite/Sulphate Injectable Bone Substitute As a Carrier for Bone Morphogenic Protein-2 and Zoledronic Acid: In- Vitro and In-Vivo Analysis
نویسندگان
چکیده
Deepak Bushan Raina, Hanna Isaksson, Werner Hettwer, Ashok Kumar, Magnus Tagil, Lars Lidgren. Lund University, Department of Orthopedics, Lund, Sweden, Lund University, Department of Biomedical Engineering, Lund, Sweden, University of Copenhagen, Department of orthopedic surgery, Copenhagen, Denmark, Indian Institute of Technology Kanpur, Department of Biological Sciences and Bioengineering, Kanpur, India.
منابع مشابه
A Biphasic Calcium Sulphate/Hydroxyapatite Carrier Containing Bone Morphogenic Protein-2 and Zoledronic Acid Generates Bone
In orthopedic surgery, large amount of diseased or injured bone routinely needs to be replaced. Autografts are mainly used but their availability is limited. Commercially available bone substitutes allow bone ingrowth but lack the capacity to induce bone formation. Thus, off-the-shelf osteoinductive bone substitutes that can replace bone grafts are required. We tested the carrier properties of ...
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